Iron is important for immune function yet it is one of the most common nutrient deficiencies. Here are many reasons why you should check iron levels at your next checkup.
Iron plays an essential role in normal development of the immune system and resistance to infection. Impaired immunocompetence is associated with iron deficiency. Ref. Ref.
Iron is necessary for immune cell production, cytokine production, ref, immune response
and the generation of reactive oxygen species required for killing pathogens. Ref Ref
Iron deficiency is associated with some reduced function of lymphoid organs (tissues that produce lymphocytes) and immune cells, specifically thymus degeneration, resulting in a decrease of T cells. Ref.
Iron deficiency is associated with reduced neutrophil activity against bacteria. Myeloperoxidase, an enzyme in neutrophils required for killing bacteria, needs iron to function. Ref.
Low iron is linked to changes in immune responses that reduce the ability to fight off viral and bacterial infections. Ref.
Iron deficiency is associated with impairments in cell mediated immunity and innate immunity and may render older adults more vulnerable to infections. Ref.
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